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| Name | W | L | SV | ERA | G | GS | IP | HA | R | ER | HR | BB | K | WHIP | OAVG | BABIP | WAR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Matt Thornton RP | 1 | 1 | 2 | 1.59 | 13 | 0 | 22.2 | 9 | 4 | 4 | 1 | 3 | 14 | 0.53 | .127 | .140 | 0.6 |
| Rube Marquard RP | 1 | 0 | 0 | 1.64 | 7 | 1 | 11.0 | 7 | 2 | 2 | 2 | 2 | 15 | 0.82 | .179 | .227 | 0.2 |
| Dustin Hermanson RP | 0 | 0 | 0 | 1.64 | 6 | 0 | 11.0 | 10 | 2 | 2 | 0 | 3 | 15 | 1.18 | .244 | .385 | 0.6 |
| Jimmy Key SP | 1 | 0 | 0 | 2.00 | 1 | 1 | 9.0 | 7 | 2 | 2 | 1 | 0 | 8 | 0.78 | .200 | .231 | 0.4 |
| Joe Thatcher CL | 3 | 3 | 9 | 2.32 | 26 | 0 | 31.0 | 26 | 9 | 8 | 2 | 17 | 31 | 1.39 | .226 | .286 | 0.9 |
| Trevor Rosenthal RP | 1 | 1 | 0 | 2.42 | 16 | 0 | 22.1 | 13 | 6 | 6 | 4 | 6 | 20 | 0.85 | .178 | .180 | 0.2 |
| Jock Menefee SP | 5 | 2 | 2 | 2.44 | 10 | 7 | 55.1 | 43 | 16 | 15 | 6 | 10 | 54 | 0.96 | .212 | .255 | 1.9 |
| Phil Stremmel RP | 1 | 0 | 0 | 2.45 | 15 | 1 | 36.2 | 34 | 11 | 10 | 2 | 8 | 24 | 1.15 | .245 | .283 | 0.8 |
| Mike Kume RP | 0 | 0 | 0 | 2.70 | 8 | 0 | 20.0 | 15 | 6 | 6 | 0 | 6 | 15 | 1.05 | .205 | .259 | 0.5 |
| Al Alburquerque RP | 0 | 0 | 0 | 3.38 | 6 | 0 | 10.2 | 7 | 4 | 4 | 1 | 6 | 9 | 1.22 | .194 | .231 | 0.1 |
| Adam Russell RP | 0 | 0 | 0 | 3.77 | 9 | 0 | 14.1 | 14 | 7 | 6 | 2 | 13 | 11 | 1.88 | .259 | .293 | -0.1 |
| Clay Hensley RP | 2 | 1 | 1 | 4.32 | 14 | 0 | 25.0 | 23 | 14 | 12 | 3 | 10 | 26 | 1.32 | .237 | .294 | 0.4 |
| Sheriff Blake SP | 3 | 2 | 0 | 4.33 | 5 | 5 | 35.1 | 34 | 18 | 17 | 6 | 12 | 33 | 1.30 | .248 | .283 | 0.7 |
| Bob Gibson SP | 2 | 3 | 0 | 4.44 | 8 | 7 | 48.2 | 40 | 27 | 24 | 11 | 20 | 44 | 1.23 | .216 | .223 | 0.3 |
| Adam Wainwright SP | 8 | 13 | 0 | 4.54 | 22 | 22 | 150.2 | 146 | 78 | 76 | 26 | 55 | 128 | 1.33 | .255 | .286 | 1.9 |
| Matt Morris SP | 1 | 0 | 0 | 4.76 | 4 | 4 | 22.2 | 26 | 13 | 12 | 2 | 7 | 16 | 1.46 | .310 | .353 | 0.5 |
| Mickey Welch SP | 1 | 7 | 0 | 4.99 | 10 | 10 | 66.2 | 59 | 38 | 37 | 19 | 28 | 53 | 1.30 | .237 | .225 | -0.3 |
| Joe Blong SP | 2 | 1 | 0 | 5.19 | 3 | 3 | 17.1 | 20 | 10 | 10 | 2 | 5 | 22 | 1.44 | .286 | .383 | 0.6 |
| Jim Bibby RP | 3 | 2 | 0 | 5.87 | 7 | 6 | 38.1 | 47 | 25 | 25 | 11 | 12 | 32 | 1.54 | .307 | .327 | -0.1 |
| Jake Westbrook SP | 5 | 8 | 0 | 5.91 | 19 | 17 | 112.2 | 146 | 76 | 74 | 28 | 33 | 93 | 1.59 | .317 | .345 | 0.5 |
| Jack McDowell RP | 1 | 0 | 0 | 6.10 | 8 | 1 | 20.2 | 17 | 14 | 14 | 7 | 9 | 29 | 1.26 | .221 | .244 | -0.2 |
| Marcus Stroman SP | 4 | 8 | 0 | 6.85 | 17 | 15 | 94.2 | 116 | 73 | 72 | 20 | 30 | 77 | 1.54 | .311 | .343 | 0.7 |
| A. J. Schugel RP | 1 | 0 | 0 | 8.68 | 5 | 0 | 9.1 | 14 | 10 | 9 | 4 | 5 | 8 | 2.04 | .341 | .345 | -0.3 |
| Jeremy Bonderman RP | 1 | 0 | 0 | 10.61 | 5 | 0 | 9.1 | 17 | 12 | 11 | 4 | 2 | 6 | 2.04 | .378 | .361 | -0.3 |
| Ramiro Mendoza RP | 0 | 1 | 0 | 12.00 | 3 | 0 | 3.0 | 4 | 4 | 4 | 1 | 4 | 4 | 2.67 | .364 | .500 | -0.1 |
