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| Name | W | L | SV | ERA | G | GS | IP | HA | R | ER | HR | BB | K | WHIP | OAVG | BABIP | WAR |
|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|---|
| Mike Kume RP | 4 | 1 | 0 | 1.95 | 22 | 0 | 32.1 | 20 | 9 | 7 | 1 | 15 | 23 | 1.08 | .187 | .229 | 0.7 |
| Eddie Guardado RP | 2 | 3 | 2 | 2.53 | 47 | 0 | 46.1 | 37 | 13 | 13 | 6 | 9 | 42 | 0.99 | .214 | .248 | 1.0 |
| Lee Smith CL | 1 | 1 | 0 | 2.66 | 20 | 0 | 20.1 | 9 | 6 | 6 | 1 | 8 | 24 | 0.84 | .130 | .182 | 0.9 |
| A. Rube Foster SP | 11 | 8 | 0 | 3.30 | 40 | 24 | 204.1 | 133 | 84 | 75 | 15 | 75 | 151 | 1.02 | .189 | .219 | 6.0 |
| Craig Kimbrel CL | 5 | 5 | 15 | 3.40 | 49 | 0 | 45.0 | 28 | 17 | 17 | 5 | 23 | 50 | 1.13 | .182 | .232 | 1.2 |
| Jock Menefee SP | 0 | 1 | 0 | 3.68 | 6 | 0 | 7.1 | 5 | 3 | 3 | 1 | 0 | 6 | 0.68 | .185 | .200 | 0.2 |
| Frank DiPino CL | 3 | 1 | 2 | 3.81 | 48 | 0 | 54.1 | 55 | 24 | 23 | 8 | 18 | 45 | 1.34 | .271 | .311 | 0.8 |
| Smokey Joe Wood SP | 15 | 12 | 0 | 4.11 | 31 | 30 | 190.2 | 154 | 102 | 87 | 23 | 61 | 177 | 1.13 | .221 | .260 | 5.2 |
| Dustin Hermanson RP | 2 | 3 | 0 | 4.45 | 26 | 0 | 30.1 | 29 | 20 | 15 | 7 | 18 | 26 | 1.55 | .254 | .272 | -0.2 |
| Adam Wainwright SP | 1 | 3 | 1 | 4.66 | 8 | 4 | 29.0 | 25 | 15 | 15 | 5 | 12 | 23 | 1.28 | .234 | .250 | 0.4 |
| Matt Morris SP | 1 | 1 | 0 | 4.85 | 8 | 4 | 26.0 | 22 | 14 | 14 | 4 | 14 | 17 | 1.38 | .232 | .240 | 0.3 |
| Joe Beggs SP | 1 | 2 | 0 | 5.06 | 9 | 1 | 16.0 | 15 | 9 | 9 | 4 | 4 | 12 | 1.19 | .242 | .239 | 0.1 |
| José Rijo SP | 8 | 12 | 0 | 5.09 | 31 | 30 | 178.2 | 162 | 105 | 101 | 40 | 63 | 154 | 1.26 | .243 | .255 | 2.2 |
| Bob Shawkey SP | 4 | 4 | 0 | 5.10 | 47 | 2 | 100.2 | 97 | 65 | 57 | 29 | 43 | 88 | 1.39 | .257 | .259 | -0.6 |
| Frank Castillo SP | 12 | 7 | 0 | 5.21 | 34 | 33 | 193.1 | 186 | 118 | 112 | 37 | 69 | 158 | 1.32 | .250 | .271 | 3.1 |
| Luke Hamlin SP | 6 | 12 | 0 | 5.55 | 28 | 24 | 147.2 | 172 | 103 | 91 | 37 | 43 | 106 | 1.46 | .292 | .299 | 1.2 |
| Jeff Pfeffer SP | 1 | 4 | 16 | 6.16 | 43 | 0 | 49.2 | 59 | 34 | 34 | 9 | 17 | 41 | 1.53 | .303 | .338 | 0.2 |
| Bob Gibson SP | 2 | 4 | 0 | 6.82 | 18 | 11 | 64.2 | 64 | 52 | 49 | 16 | 35 | 46 | 1.53 | .262 | .259 | -0.2 |
